Tohoku J. Exp. Med., 1999, 187 (3)

Case Report

Prenatal Confirmation of the Translocation between Chromosome 15 and Y-Chromosome by Fluorescence in situ Hybridization

YUKIHITO FUKADA, TAKEHIKO YASUMIZU, ATSUHITO AMEMIYA, KEIKO KOHNO, MOTOI TAKIZAWA and KAZUHIKO HOSHI

Department of Obstetrics and Gynecology, Yamanashi Medical University, Yamanashi 409-3898

  • A 30-year-old woman and her husband visited our hospital with habitual abortion as the complaint. Chromosome examination revealed a normal 46, XX for her and 46, XY, -15, der (15) t (Y; 15) (q12; p12) for him. After her pregnancy amniocentesis was performed. The karyotype was 46, XX, -15, der (15) t (Y; 15) (q12; p12) pat. ish der (15) (DYZ1+). A female baby was delivered. The growth of the baby was normal at 12 months of age.
    Key words--- chromosome 15 and Y translocation; fluorescence in situ hybridization (FISH); uncultured amniotic fluid cells; prenatal diagnosis
    © 1999 Tohoku University Medical Press

    Tohoku J. Exp. Med., 1999, 187, 285-289
    Address for reprints: Yukihito Fukada, Department of Obstetrics and Gynecology, Yamanashi Medical University, 1110 Shimokato, Tamaho, Nakakoma-gun, Yamanashi 409-3898, Japan.
    e-mail: yfukada@res.yamanashi-med.ac.jp

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