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Top 30 Articles Most Frequently Cited: 1920-2020

(Data as of June 30, 2020)

Times Cited Article
[1] 341 Kyoichi Shimomura, Osamu Kamata, Showa Ueki, Seiu Ida, Kazuta Oguri, Hidetoshi Yoshimura and Hisao Tsukamoto. “Analgesic Effect of Morphine Glucuronides.” (1971) Sep. 105 (1) 45-52.
[2] 267 Yoshio Goto, Masaei Kakizaki and Naoyoshi Masaki. “Production of Spontaneous Diabetic Rats by Repetition of Selective Breeding.” (1976) May 119 (1) 85-90.
[3] 265 Michiko Furuyama. “Histometrical Investigations of Arteries in Reference to Arterial Hypertension.” (1962) May 76 (4) 388-414.
[4] 220 Masao Sato and Masuo Kondoh. “Recent Studies on Metallothionein: Protection Against Toxicity of Heavy Metals and Oxygen Free Radicals.” (2002) Jan. 196 (1) 9-22. [Review]
[5] 176 Osamu Suzuki, Masanori Nakamura, Yoshinori Miyasaka, Manabu Kagayama and Minoru Sakurai. “Bone Formation on Synthetic Precursors of Hydroxyapatite.” (1991) May 164 (1) 37-50.
[6] 173 Leonard P Rybak, Debashree Mukherjea, Sarvesh Jajoo and Vickram Ramkumar. “Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies.” (2009) Nov. 219 (3) 177-186. [Invited Review for the 90th Anniversary]
[7] 163 Noboru Nakano. “Establishment of Cell Lines in vitro from a Mammary Ascites Tumor of Mouse and Biological Properties of the Sstablished Lines in a Serum Containing Medium.” (1966) Jan. 88 (1) 69-84.
[8] 159 Tadashi Terada and Masaharu Kawaguchi. “Primary Clear Cell Adenocarcinoma of the Peritoneum.” (2005) Jul. 206 (3) 271-275. [Case]
[9] 149 Chang-Wan Han, Eun-Joo Lee, Tsutomu Iwaya, Hitomi Kataoka and Masahiro Kohzuki. “Development of the Korean Version of Short-Form 36-Item Health Survey: Health Related QOL of Healthy Elderly People and Elderly Patients in Korea.” (2004) Jul. 203 (3) 189-194.
[10] 135 Kazumichi Furuyama, Kiriko Kaneko and Patrick D. Vargas V. “Heme as a Magnificent Molecule with Multiple Missions: Heme Determines Its Own Fate and Governs Cellular Homeostasis.” (2007) Sep. 213 (1) 1-16. [Invited Review]
[11] 119 Shigeki Shibahara. “The Heme Oxygenase Dilemma in Cellular Homeostasis: New Insights for the Feedback Regulation of Heme Catabolism.” (2003) Aug. 200 (4) 167-186. [Invited Review]
[12] 119 Yoshiaki Yajima, Kei Ohta, Takashi Narui, Ryuzo Abe, Hiroshi Suzuki and Masao Ohtsuki. “Ultrasonographical Diagnosis of Fatty Liver: Significance of the Liver-Kidney Contrast.” (1983) Jan. 139 (1) 43-50.
[13] 108 Susumu Saijyo, Toshio Kudo, Masanori Suzuki, Yu Katayose, Masao Shinoda, Taisei Muto, Kenji Fukuhara, Takao Suzuki and Seiki Matsuno. “Establishment of a New Extrahepatic Bile Duct Carcinoma Cell Line, TFK-1.” (1995) Sep. 177 (1) 61-71.
[14] 108 Ken Saito, Nobuhisa Yaginuma and Tohru Takahashi. “Differental Volumetry of A, B and D Cells in the Pancreatic Islets of Diabetic and Nondiabetic Subjects.” (1979) Nov. 129 (3) 273-283.
[15] 107 Toshiyuki Takahashi, Kazuo Fujihara, Ichiro Nakashima, Tatsuro Misu, Isabelle Miyazawa, Masashi Nakamura, Shohei Watanabe, Naoto Ishii and Yasuto Itoyama. “Establishment of a New Sensitive Assay for Anti-Human Aquaporin-4 Antibody in Neuromyelitis Optica.” (2006) Dec. 210 (4) 307-313.
[16] 107 Mehmet Kanter, Ismail Meral, Zabit Yener, Hanefi Ozbek and Halit Demir. “Partial Regeneration/Proliferation of the -Cells in the Islets of Langerhans by Nigella Sativa L. in Streptozotocin-Induced Diabetic Rats.” (2003) Dec. 201 (4) 213-219.
[17] 104 Norio Suwa, Takashi Niwa, Hitoshi Fukasawa and Yasuhiko Sasaki. “Estimation of Intravascular Blood Pressure Gradient by Mathematical Analysis of Arterial Casts.” (1963) Mar. 79 (2) 168-198.
[18] 100 Duygu Gezen-Ak, ErdinEDursun, Turan Ertan, Hasmet Hanagasi, Hakan GEvit, Murat Emre, Engin Eker, Melek ztEk, Funda Engin and Selma Yilmazer. “Association between Vitamin D Receptor Gene Polymorphism and Alzheimer’s Disease.” (2007) Jul. 212 (3) 275-282.
[19] 95 Yihe Jin, Norimitsu Saito, Kouji H. Harada, Kayoko Inoue and Akio Koizumi. “Historical Trends in Human Serum Levels of Perfluorooctanoate and Perfluorooctane Sulfonate in Shenyang, China.” (2007) May 212 (1) 63-70.
[20] 93 Hiroki Watanabe, Dairoku Igari, Yoshikatsu Tanahashi, Kazuya Harada and Masahito Saitoh. “Measurements of Size and Weight of Prostate by Means of Transrectal Ultrasonotomography.” (1974) Nov. 114 (3) 277-285.
[21] 92 Ki Hun Cho, Kyoung Jin Lee and Chang Ho Song. “Virtual-Reality Balance Training with a Video-Game System Improves Dynamic Balance in Chronic Stroke Patients.” (2012) Sep. 228 (1) 69-74.
[22] 90 Xuan Hong, Baohong Cui, Meng Wang, Zhaoyang Yang, Li Wang and Qingyong Xu. “Systemic Immune-inflammation Index, Based on Platelet Counts and Neutrophil-Lymphocyte Ratio, Is Useful for Predicting Prognosis in Small Cell Lung Cancer.” (2015) Aug. 236 (4) 297-304.
[23] 90 Shigeki Shibahara, Yasushi Tomita, Hachiro Tagami, Rita M. MEler and Tirza Cohen. “Molecular Basis for the Heterogeneity of Human Tyrosinase.” (1988) Dec. 156 (4) 403-414.
[24] 89 Bunsho Lee, Yuetsu Tanaka and Hideki Tozawa. “Monoclonal Antibody Defining Tax1 Protein of Human T-Cell Leukemia Virus Type-I.” (1989) Jan. 157 (1) 1-11.
[25] 88 Seiichiro Nagai, Tadashi Mabuchi, Shuji Hirata, Tomoko Shoda, Tsuyoshi Kasai, Sadaki Yokota, Hiroshi Shitara, Hiromichi Yonekawa and Kazuhiko Hoshi. “Correlation of Abnormal Mitochondrial Distribution in Mouse Oocytes with Reduced Developmental Competence.” (2006) Oct. 210 (2) 137-144.
[26] 87 Tatsuro Misu, Kazuo Fujihara, Masashi Nakamura, Kazuhiro Murakami, Minoru Endo, Hidehiko Konno and Yasuto Itoyama. “Loss of Aquaporin-4 in Active Perivascular Lesions in Neuromyelitis Optica: A Case Report.” (2006) Jul. 209 (3) 269-275. [Case]
[27] 86 Toshitaka Nabeshima and Atsumi Nitta. “Memory Impairment and Neuronal Dysfunction Induced by -Amyloid Protein in Rats.” (1994) Nov. 174 (3) 241-249.
[28] 85 Chiho Watanabe. “Modification of Mercury Toxicity by Selenium: Practical Importance?” (2002) Feb. 196 (2) 71-77. [Review]
[29] 84 Akira Yasutake, Miyuki Matsumoto, Masako Yamaguchi and Noriyuki Hachiya. “Current Hair Mercury Levels in Japanese: Survey in Five Districts.” (2003) Mar. 199 (3) 161-169.
[30] 84 Kosei Ishii, Kazumasa Honda and Kazuko Ishii. “The Function of Carotid Labyrinth in the Toad.” (1966) Feb. 88 (2) 103-116.


Remarks: Since 1920, each article of TJEM was written in one of three languages, German, English, and French. In 1956 (from Volume 64), English was determined as the sole official language in TJEM. 



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